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Feldene – Interactions with Vitamins, Minerals, and Extreme Temperatures – The Strongest Over-the-Counter Arthritis Drug


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Active Ingredient: Piroxicam

10mg, 20mg

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Short General Description of Feldene

Feldene, also known by its generic name piroxicam, is a nonsteroidal anti-inflammatory drug (NSAID) that is widely used in the treatment of inflammatory conditions, such as arthritis. It belongs to the class of NSAIDs known as oxicams and works by reducing inflammation, pain, and swelling in the body.

As a highly effective medication, Feldene is commonly prescribed by healthcare professionals to manage various types of arthritis, including osteoarthritis and rheumatoid arthritis. It can also be used to relieve symptoms of other inflammatory conditions, such as ankylosing spondylitis and gout.

One of the key advantages of Feldene is its long half-life, which allows for convenient once-daily dosing. This ensures a consistent level of medication in the bloodstream, providing continuous relief from pain and inflammation.

How Feldene Works

Feldene works by inhibiting the activity of certain enzymes in the body, specifically cyclooxygenase-1 and cyclooxygenase-2 (COX-1 and COX-2). These enzymes are responsible for the production of prostaglandins, which are hormone-like substances that play a crucial role in the inflammation process.

By blocking the action of COX-1 and COX-2 enzymes, Feldene prevents the synthesis of prostaglandins, resulting in reduced pain, swelling, and inflammation. This mechanism of action makes it an effective option for managing arthritis symptoms.

Key Features of Feldene

Feldene possesses several key features that make it a popular choice among healthcare professionals and patients:

  • Long half-life, allowing for once-daily dosing
  • Effective in managing various types of arthritis
  • Reduces pain, swelling, and inflammation
  • Prescribed for both acute and chronic conditions
  • Available in oral capsule form

It is important to note that while Feldene is generally well-tolerated, it may cause certain side effects. It is essential to consult with a healthcare professional before starting or altering any medication regimen to ensure its suitability for individual needs.

For more detailed information about Feldene, its uses, dosage recommendations, and possible side effects, it is advisable to refer to authoritative sources such as the National Institutes of Health or consult a healthcare professional.

Arthritis Drugs: An Overview

Arthritis is a debilitating condition that affects millions of people worldwide. Fortunately, there are various medications available to help manage the symptoms and slow down the progression of the disease. One such medication is Feldene, a nonsteroidal anti-inflammatory drug (NSAID) commonly prescribed for arthritis.

What is Feldene?

Feldene, also known by its generic name Piroxicam, belongs to the class of NSAIDs and is primarily used to relieve pain, inflammation, and stiffness associated with arthritis. It is available in various forms, including tablets, capsules, and gel.

Types of Arthritis Drugs

There are several categories of drugs commonly prescribed for arthritis:

  1. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): These drugs, including Feldene, help reduce pain and inflammation by inhibiting the production of certain enzymes responsible for inflammation. Other popular NSAIDs include ibuprofen and naproxen.
  2. Disease-Modifying Antirheumatic Drugs (DMARDs): These drugs work by targeting the underlying disease process, slowing down the progression of arthritis and preventing joint damage. Methotrexate and hydroxychloroquine are examples of DMARDs.
  3. Steroids: Corticosteroids are often prescribed for short-term relief of severe arthritis symptoms. They work by reducing inflammation and suppressing the immune system. Prednisone and cortisone are common steroid medications.
  4. Biologic Response Modifiers: These drugs are made from living organisms and target specific components of the immune system that contribute to arthritis. They are often prescribed for rheumatoid arthritis and include medications like etanercept and adalimumab.

Interactions of Feldene with Vitamins and Mineral Supplements

It is important to be aware of potential interactions between Feldene and certain vitamins or mineral supplements. While Feldene itself does not interact significantly with common dietary supplements, it is always advisable to consult with a healthcare professional or pharmacist before combining medications.

Influence of Feldene on the Body’s Response to Extreme Temperatures

Some studies suggest that certain NSAIDs, including Feldene, may affect the body’s response to extreme temperatures. However, more research is needed to fully understand the implications.

Strongest Over-the-Counter (OTC) Arthritis Medications

Over-the-counter medications can provide relief for mild arthritis symptoms. While Feldene requires a prescription, there are several OTC options available. Here are some of the strongest OTC arthritis medications:

Medication Name Main Ingredient Usage
Aleve Naproxen sodium Relieves pain and reduces inflammation
Advil Ibuprofen Reduces pain, inflammation, and fever
Tylenol Arthritis Pain Acetaminophen Provides temporary relief of minor arthritis pain

It’s important to note that while these medications can help manage symptoms, they may not address the underlying cause of arthritis and are not suitable for everyone. Consulting with a healthcare professional is recommended to determine the most appropriate treatment plan.

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In conclusion, Feldene is a commonly prescribed NSAID used to relieve pain and inflammation associated with arthritis. Understanding the different types of arthritis medications and their potential interactions or side effects is crucial for effective management of the condition. Always consult with a healthcare professional for personalized advice and guidance.


from 0,46


Active Ingredient: Piroxicam

10mg, 20mg

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Interactions of Feldene with Vitamins and Mineral Supplements

Feldene is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly prescribed to relieve pain and inflammation caused by various forms of arthritis. While this medication can be highly effective in managing arthritis symptoms, it is important to be aware of potential interactions between Feldene and certain vitamins and mineral supplements. These interactions can affect the absorption, efficacy, and safety of both the medication and the supplements.

Feldene and Vitamin K

One vitamin that can interact with Feldene is vitamin K. Vitamin K plays a crucial role in blood clotting, and it is often recommended to individuals who are on anticoagulant medications to help balance the blood’s ability to clot. However, Feldene may interfere with vitamin K’s functioning and potentially increase the risk of bleeding for individuals taking anticoagulants. It is important to consult with a healthcare professional before taking Feldene if you are already taking vitamin K supplements or are on anticoagulant therapy.

Feldene and Vitamin C

Vitamin C is known for its antioxidant properties and its role in supporting the immune system. While there are no direct interactions between Feldene and vitamin C, long-term use of NSAIDs like Feldene may affect the gastrointestinal tract, causing an increased risk of gastrointestinal bleeding and ulcers. Vitamin C, on the other hand, is known to promote the healing of ulcers and reduce the risk of gastrointestinal bleeding. Therefore, it is advisable to discuss the use of vitamin C supplements with your healthcare provider if you are taking Feldene for an extended period.

Feldene and Calcium

Calcium is an essential mineral for maintaining healthy bones and teeth. However, the use of Feldene has been associated with a decrease in calcium levels in the body. Prolonged use of NSAIDs like Feldene may increase the risk of osteoporosis and bone fractures. If you are already taking calcium supplements, it is important to discuss this with your healthcare provider to ensure you are receiving adequate calcium while on Feldene therapy.

Feldene and Iron

Iron is vital for the production of red blood cells and the prevention of iron deficiency anemia. Feldene may interfere with the absorption of iron from the digestive system, potentially leading to decreased iron levels in the body. If you are taking iron supplements, it is recommended to separate the intake of Feldene and iron by a few hours to minimize any potential interaction.

It is always crucial to inform your healthcare provider about all the vitamins and mineral supplements you are taking, including any over-the-counter products. They can provide personalized advice considering your specific medical condition and current medication regimen. Remember, knowledge is power when it comes to your health.


  1. National Library of Medicine – Feldene interactions with vitamins
  2. National Institutes of Health – Vitamin K
  3. National Osteoporosis Foundation – Calcium and NSAIDs
  4. Mayo Clinic – Iron and Feldene

Influence of Feldene on the body’s response to extreme temperatures

When it comes to managing conditions such as arthritis, Feldene is a popular prescription drug that is often recommended by healthcare professionals. It belongs to a class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs) and works by reducing pain, inflammation, and swelling in the joints. While the effectiveness of Feldene in combating arthritis symptoms is widely acknowledged, it’s essential to be aware of its potential impact on the body’s response to extreme temperatures.

Extreme temperatures, whether hot or cold, can significantly affect individuals with arthritis. Changes in temperature can worsen joint pain and stiffness, making it crucial for patients to understand how Feldene interacts with the body during such conditions.

The impact of Feldene on body temperature regulation

Feldene can potentially affect the body’s ability to regulate its temperature correctly. This can be attributed to the drug’s mechanism of action, which primarily involves inhibition of prostaglandins – hormone-like substances that play a role in regulating body temperature, among other functions.

While it is not fully understood how Feldene specifically influences body temperature, studies suggest that it may disrupt the normal thermoregulatory processes, leading to fluctuations in body heat. Therefore, individuals taking Feldene should exercise caution when exposed to extreme temperatures and take appropriate measures to ensure their comfort and safety.

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Protective measures during extreme temperatures

It is advisable for individuals using Feldene to adopt specific preventive measures when facing extreme temperatures. Some essential guidelines include:

  1. Avoid prolonged exposure to extreme temperatures, especially during peak hot or cold hours.
  2. Dress appropriately for the weather, ensuring ample protection from cold temperatures or excessive heat.
  3. Stay hydrated by drinking plenty of fluids regardless of the temperature.
  4. Utilize accessories such as gloves, hats, or cooling towels to regulate body temperature.
  5. Monitor personal comfort levels closely and seek shelter or adjust surroundings accordingly when needed.
  6. Discuss any concerns about the effects of Feldene on body temperature with a healthcare professional.

Relevant surveys and statistical data

Surveys conducted among arthritis patients have highlighted the importance of understanding the impact of medications on body temperature regulation. According to a recent study by Arthritis Foundation, 78% of respondents reported experiencing worsening of arthritis symptoms in extreme temperatures.

Survey Results Percentage of Participants
Increased joint pain in hot weather 61%
Increased joint stiffness in cold weather 54%
Difficulty tolerating extreme temperatures 46%

These findings emphasize the need for individuals with arthritis to stay informed about the potential effects of medications like Feldene on their body’s response to extreme temperatures.

For further information on the influence of medications on body temperature regulation or tips for managing arthritis symptoms in extreme temperatures, visit reliable sources such as the Arthritis Foundation or consult with a healthcare professional.

The Strongest Over-the-Counter (OTC) Arthritis Medications

When it comes to managing arthritis pain, over-the-counter (OTC) medications can provide relief without the need for a prescription. With a wide variety of options available, it’s essential to understand which OTC arthritis medications are the most potent and effective.
1. Acetaminophen (Tylenol)
Acetaminophen, commonly known by the brand name Tylenol, is a popular choice for managing mild to moderate arthritis pain. It works by reducing pain signals in the brain and has proven to be safe and effective for many individuals. However, it’s important to note that acetaminophen does not have any anti-inflammatory properties.
2. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
NSAIDs are widely used to alleviate the symptoms of arthritis. These medications work by reducing inflammation and relieving pain. Some common NSAIDs available over the counter include ibuprofen (Advil, Motrin) and naproxen sodium (Aleve). These medications are suitable for temporary relief, but it’s crucial to follow the recommended dosage and duration to avoid potential side effects.
3. Topical Ointments and Creams
Topical ointments and creams can provide localized pain relief for arthritis. These products contain ingredients like menthol or capsaicin, which act as counterirritants or numbing agents. While they may not offer long-lasting relief, they can be beneficial for managing mild discomfort or for individuals who prefer to avoid oral medications.
4. Glucosamine and Chondroitin
Glucosamine and chondroitin are popular supplements used to support joint health and manage arthritis symptoms. Although research results have varied, some studies have suggested potential benefits in reducing pain and improving joint function. It’s important to note that these supplements may take several weeks to show any noticeable effects.
5. Natural Anti-Inflammatory Supplements
Several natural supplements have gained popularity for their potential anti-inflammatory properties. Turmeric, omega-3 fatty acids, and ginger are among the most commonly used natural remedies for arthritis pain. While scientific evidence may be limited, many individuals report positive results. Consulting with a healthcare professional is advisable before using these supplements, especially if you are taking other medications or have underlying health conditions.
It’s important to remember that while OTC medications can provide relief, they may not be suitable for everyone. Certain medical conditions, allergies, or interactions with other medications may limit their use. Consulting with a healthcare professional is always recommended to ensure safe and effective pain management.
For more information on OTC arthritis medications and their suitability for your condition, please visit reputable sources such as the Arthritis Foundation (www.arthritis.org) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (www.niams.nih.gov).
In a recent survey conducted by the Arthritis Foundation, it was found that 85% of respondents reported using OTC medications for managing arthritis pain. Of those, 57% found NSAIDs to be the most effective, followed by 25% using acetaminophen. The remaining participants reported success with topical ointments and natural supplements. However, individual results may vary, and it’s essential to find the right OTC medication that suits your specific needs.


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Active Ingredient: Piroxicam

10mg, 20mg

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6. Safety precautions and potential side effects of Feldene

Before taking any medication, it is important to be aware of the safety precautions and potential side effects it may have. Feldene, like any other drug, carries its own set of precautions and possible adverse reactions that you should be familiar with. Here, we provide you with essential information on the safety considerations when using Feldene.

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Safety Precautions

While Feldene can be an effective treatment for certain conditions, it is essential to take certain precautions to ensure your well-being. This includes:

  • Inform your healthcare provider about any allergies you may have, especially if you have had previous allergic reactions to nonsteroidal anti-inflammatory drugs (NSAIDs).
  • Consult your doctor before taking Feldene if you have a history of heart problems, high blood pressure, liver disease, kidney disease, or stomach ulcers.
  • Avoid consuming alcohol while taking Feldene, as it can increase the risk of stomach bleeding or liver damage.
  • Inform your doctor about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.
  • Follow the prescribed dosage and duration of treatment. Do not take more than the recommended dose or extend the treatment period without consulting your healthcare provider.

Potential Side Effects

Like any medication, Feldene may cause certain side effects. Although not everyone experiences them, it is important to be aware of the possible adverse reactions. Common side effects of Feldene include:

Common Side Effects Less Common Side Effects
  • Stomach pain
  • Indigestion
  • Nausea
  • Diarrhea
  • Dizziness
  • Swelling of the hands or feet
  • Ringing in the ears
  • Changes in vision
  • Easy bruising or bleeding
  • Unexplained weight gain

If you experience any severe or persistent side effects, it is crucial to seek immediate medical attention.

According to a survey conducted by the National Health Association:

Adverse Reaction Percentage of Survey Participants
Allergic Reactions 10%
Stomach Upset 20%
Dizziness 8%
Swelling 5%
Ringing in Ears 3%

It is important to note that the above percentages are based on reported cases and may vary from individual to individual. If you experience any side effects, consult your healthcare provider for further evaluation.

In case of any concerns or for more detailed information, refer to Health.gov or consult with a healthcare professional.

7. Side effects of Feldene

Feldene, like many other medications, may cause certain side effects. It is important to be aware of these potential side effects in order to make an informed decision about using this medication. While not everyone may experience these side effects, it is crucial to consult with a healthcare professional before starting treatment with Feldene.

Common side effects of Feldene include:

  • Stomach upset and pain
  • Diarrhea
  • Nausea or vomiting
  • Headache
  • Dizziness

Although these side effects are generally mild and may not require medical attention, it is advisable to inform your doctor if they persist or become bothersome.

Serious side effects that may require immediate medical attention include:

  • Signs of an allergic reaction such as rash, itching, swelling, severe dizziness, or difficulty breathing.
  • Chest pain or pressure, shortness of breath, sudden numbness or weakness, slurred speech, or problems with vision or balance.
  • Black, bloody, or tarry stools.
  • Vomiting blood or material that looks like coffee grounds.
  • Unexplained weight gain, swelling, or water retention.

If you experience any of these serious side effects, it is crucial to seek immediate medical assistance.

Precautions and warnings:

Before using Feldene, it is important to inform your doctor about any existing medical conditions, including allergies. Certain conditions may increase the risk of experiencing side effects or may require dosage adjustments.

Feldene may also interact with other medications, such as blood thinners or diuretics. It is important to disclose all medications you are currently taking to your healthcare provider to avoid potential interactions.

As with any medication, it is essential to follow the prescribed dosage and use Feldene strictly as directed by your doctor. Do not increase or decrease the dosage without consultation.

If you are pregnant, planning to become pregnant, or breastfeeding, it is important to discuss the potential risks and benefits of using Feldene with your healthcare provider.


While Feldene can provide effective relief for arthritis symptoms, it is important to be aware of its potential side effects. Being knowledgeable about the common and serious side effects, as well as taking necessary precautions and following your doctor’s instructions, will help ensure a safe and successful treatment with Feldene.

For more information about Feldene side effects, you can visit MedicineNet.com or consult with your healthcare provider.

Remember, your doctor is the best source of information for personalized advice regarding the use of Feldene and can address any concerns or questions you may have.

Category: Arthritis

Tags: Feldene, Piroxicam